Urrutia, Victor

Medicine - Neurology

Peru

External Bio Page

Establishment of stroke incidence and links to household air pollution

The World Health Organization (WHO) has identified stroke as a high public health priority in low- and middle-income countries (LMICs) (1). Stroke prevalence and related risk factors unique to LMICs are not well identified.  Household air pollution (HAP) from exposure to biomass fuel smoke is believed to be a highly prevalent risk factor that likely contributes to cerebrovascular disease (2). The WHO has estimated that nearly one quarter of all premature deaths due to stroke (i.e. 1.4 million deaths of which half are in women) can be attributed to the chronic exposure to HAP caused by cooking with biomass fuel (2), however, evidence to support this is lacking. We hypothesize, that through evaluation of stroke prevalence and establishment of a longitudinal registry to study stroke incidence in Puno, Peru, a region with high utilization (>95%) of biomass fuels for cooking in rural settings, we will be able to evaluate the association between stroke risk and exposure to HAP.  Further, we hypothesize that the Framingham Stroke Profile (FSP) will predict the increased prevalence and incidence of stroke in this population. The FSP has not been validated in Latin America. We aim to characterize the relationship between HAP and stroke to better describe the epidemiology of this potentially important risk factor in LMICs. We propose a two-year project in which we start with a cross-sectional study to evaluate stroke prevalence in Puno, Peru; and develop a continuous prospective stroke registry to determine the stroke incidence in this population. Laying the foundation for an ongoing research operation will provide the capacity to conduct intervention trials, for example by utilizing improved cookstoves to reduce stroke risk.

Will Checkley, Catherine Hooper, Kiran Thakur, Jaime Miranda

People

Joanne Katz, ScD MS,BSc

Associate Chair, Director of Academic Programs

Noreen Hynes, MD MPH

Director, Geographic Medicine Center of the Division of Infectious Diseases

Caitlin Kennedy, PhD MPH,BA

Co-Director, MPH concentration in Social and Behavioral Sciences in Public Health; Associate Director, Center for Qualitative...

Robert Bollinger Jr., MD MPH

Director, Johns Hopkins Center for Clinical Global Health Education (CCGHE); Associate Director, Johns Hopkins Center for Global...

Stefan Baral, MD MPH,MBA,MSc

Director, Key Populations Program

Yukari C. Manabe, MD

Associate Director of Global Health Research and Innovation
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November 2017

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