TB, HIV and Infectious Disease research in India
India has the world’s largest burden of tuberculosis, 3rd highest absolute burden of HIV, and among the largest burden of antimicrobial resistant infections. Our Indo-US program has several ongoing studies in TB, HIV and infectious diseases. These include 1) the CTRIUMPH study (which comprise of longitudinal cohorts of adult and pediatric TB cases, their household contacts along with extensive biobanking for assessment of risk factors and biomarker discovery of treatment response, progression to disease respectively) which is being conducted in Pune, and Chennai; 2) The TB-DM study which is assessing impact of diabetes mellitus on TB disease outcomes (Pune), 3) The TBM KIDS trial, a trial of high dose rifampin with or without levofloxacin for children with TB meningitis, 4) Screening for cardiovascular risk factors in adults and adolescents with HIV at a public sector ART clinic, 5) Etiologies of acute febrile illness among hospitalized adults and children, 6) Multidrug-resistant TB cohort, 7) Health Care worker cohort assessing infection control and TB risk factors, and lastly 8) TB, air pollution and lung health substudies.
Global Health Mentor: Amita Gupta, MD, Deputy Director, Center for Clinical Global Health Education