Morris, Max

School of Public Health

MSPH

Brazil

Evaluation of universal antiretroviral therapy guidelines in Rio de Janeiro, Brazil

Early initiation of antiretroviral therapy (ART) is highly efficacious for improving outcomes among persons living with HIV (PLHIV) and reducing HIV transmission, and is endorsed by the World Health Organization (WHO). However, while the benefits of early ART are well established in controlled settings, the public health impact of universal HIV treatment guidelines has not been quantified in many settings. The Brazilian government released guidelines recommending universal ART for all PLHIV, regardless of CD4 count, in December 2013. Multiple citywide databases allow for comprehensive monitoring of HIV-infected patients, including surveillance databases with individual information on HIV/AIDS, mortality, and other reportable infections such as tuberculosis and hepatitis; laboratory and pharmaceutical databases with information on viral load, CD4 counts, and antiretroviral use; and electronic medical records for patients engaged in care at HIV clinics. These databases have been linked to enable epidemiologic investigation of the local HIV epidemic. Our goal is to identify HIV-infected patients who have been lost to follow-up in national surveillance databases to provide better estimates of the burden of HIV in Rio de Janeiro.

PI Mentor: Jonathan Golub

People

Caitlin Kennedy, PhD MPH,BA

Co-Director, MPH concentration in Social and Behavioral Sciences in Public Health; Associate Director, Center for Qualitative...

Yukari C. Manabe, MD

Associate Director of Global Health Research and Innovation

Joanne Katz, ScD MS,BSc

Associate Chair, Director of Academic Programs

Robert Bollinger Jr., MD MPH

Director, Johns Hopkins Center for Clinical Global Health Education (CCGHE); Associate Director, Johns Hopkins Center for Global...

Stefan Baral, MD MPH,MBA,MSc

Director, Key Populations Program

Noreen Hynes, MD MPH

Director, Geographic Medicine Center of the Division of Infectious Diseases
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September 2019

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