Lescouflair, Katerina

School of Public Health - International Health

MSPH

Democratic Republic of the Congo

Democratic Republic of the Congo-Evaluation of a Baby WASH Intervention to Reduce Environmental Enteropathy and Impaired Growth in Young Children in Democratic Republic of the Congo

The Democratic Republic of the Congo (DRC) is the second largest country in Africa. In South Kivu Province 54% of children under five years are stunted. Undernutrition is estimated to be an underlying cause of death of over half of young children globally. This decline in nutritional status is thought to be greatest during the first 2 years of life. There is a growing evidence base demonstrating an association between stunting and environmental enteropathy (EE).This disorder is defined by abnormal intestinal morphology, including villous atrophy and crypt hyperplasia, which leads to reduced intestinal barrier function and increased inflammation. EE is thought to arise from unsanitary environmental conditions that lead to repeated exposure to enteric pathogens causing chronic infections. In our recent prospective cohort study in Bangladesh, we found childhood mouthing behavior, close contact with animals, and caregiver hygiene to be important risk factors for EE and impaired growth in young children. Building on this previous work in partnership with Food for the Hungry, the objective of this project is to develop and evaluate interventions to reduce pediatric exposures to fecal pathogens and thereby reduce environmental enteropathy and impaired growth among this highly susceptible population. Johns Hopkins University will lead the formative research and prospective cohort study that will inform intervention development, and direct a randomized controlled trial of the developed intervention approaches in South Kivu, DRC.

People

Robert Bollinger Jr., MD MPH

Director, Johns Hopkins Center for Clinical Global Health Education (CCGHE); Associate Director, Johns Hopkins Center for Global...

Noreen Hynes, MD MPH

Director, Geographic Medicine Center of the Division of Infectious Diseases

Stefan Baral, MD MPH,MBA,MSc

Director, Key Populations Program

Yukari C. Manabe, MD

Associate Director of Global Health Research and Innovation

Joanne Katz, ScD MS,BSc

Associate Chair, Director of Academic Programs

Caitlin Kennedy, PhD MPH,BA

Co-Director, MPH concentration in Social and Behavioral Sciences in Public Health; Associate Director, Center for Qualitative...
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August 2019

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Projects

Building an Enabling Environment for Vaccines in India...

This project, now in its second phase, aims to create an enabling environment for vaccines in India and contribute to...

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Mpilonhle

Mpilonhle brings multi-dimensional services to adolescents in rural South Africa. Its objective is to reduce the very high...

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Nutrition Innovation Lab

"Poshan", which means good nutrition in Nepali is ongoing research that involves two interlinked large-scale research studies...

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Identification and Enumeration of Pathogens in Drinking...

CWH researchers are using polymerase chain reaction and mass spectrometry technologies to develop a microbial isolation and...

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