Lake, Mikhailia

Medicine

Residency

Argentina

Reactive Oxygen Species and Cardiac Hypertrophy

Increased Sodium-Hydrogen Exchanger (Na+/H+, NHE-1) activity has been implicated in the pathogenesis of cardiac hypertrophy that is associated with hypertension and aortic stenosis, two prevalent conditions affecting the cardiovascular system. Reactive oxygen species (ROS), Angiotensin II (Ang II), Endothelin-1 (ET-1), intracellular acidosis, have all been implicated as activators of NHE-1, and are thus at least partially responsible for the hypertrophic changes seen in hearts from patients with these conditions.

People

Yukari C. Manabe, MD

Associate Director of Global Health Research and Innovation

Caitlin Kennedy, PhD MPH,BA

Co-Director, MPH concentration in Social and Behavioral Sciences in Public Health; Associate Director, Center for Qualitative...

Joanne Katz, ScD MS,BSc

Associate Chair, Director of Academic Programs

Stefan Baral, MD MPH,MBA,MSc

Director, Key Populations Program

Noreen Hynes, MD MPH

Director, Geographic Medicine Center of the Division of Infectious Diseases

Robert Bollinger Jr., MD MPH

Director, Johns Hopkins Center for Clinical Global Health Education (CCGHE); Associate Director, Johns Hopkins Center for Global...
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December 2019

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Projects

Mpilonhle

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Building an Enabling Environment for Vaccines in India...

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Nutrition Innovation Lab

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Identification and Enumeration of Pathogens in Drinking...

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