Kinzel, Kasey

School of Public Health

MSPH

Nepal

Estimating the cost of illness for typhoid fever in Nepal: A sub-study of the Typhoid Vaccine Acceleration Consortium (TyVAC)

Typhoid fever represents a substantial epidemiologic and economic burden in Nepal, and while understanding of the disease burden is growing, data quantifying the economic burden is limited. The Typhoid Vaccine Acceleration Consortium Cost of Illness study (TyVAC-COI), led by Johns Hopkins Bloomberg School of Public Health International Vaccine Access Center as part of the broader TyVAC study led by University of Maryland and Oxford University, aims to generate new evidence on the economic burden of enteric fever (i.e., typhoid and paratyphoid fever) in Nepal. The study will estimate the cost of illness from the health care system and household perspectives and estimate the catastrophic impact on households through primary data collection. We are collecting data on health facility expenditures and utilization of health services for treating enteric fever from facility administrators, medical and non-medical staff, and laboratory technicians. We are also collecting out-of-pocket expenditures, productivity loss, and household impact data from patients with blood culture-confirmed typhoid and paratyphoid presenting to a participating study health facility using a facility-based cohort study design. This study is being conducted at two hospitals in Kathmandu (Patan Hospital and Kanti Children's Hospital), three public ward clinics, and one private clinic. Results from this study will be used to inform policy decisions on typhoid control interventions, including introducing the new Typbar typhoid conjugate vaccine.

This project is being conducted alongside a vaccine effectiveness trial, led by Oxford University.

PI Mentor: Cristina Garcia

People

Joanne Katz, ScD MS,BSc

Associate Chair, Director of Academic Programs

Yukari C. Manabe, MD

Associate Director of Global Health Research and Innovation

Noreen Hynes, MD MPH

Director, Geographic Medicine Center of the Division of Infectious Diseases

Stefan Baral, MD MPH,MBA,MSc

Director, Key Populations Program

Robert Bollinger Jr., MD MPH

Director, Johns Hopkins Center for Clinical Global Health Education (CCGHE); Associate Director, Johns Hopkins Center for Global...

Caitlin Kennedy, PhD MPH,BA

Co-Director, MPH concentration in Social and Behavioral Sciences in Public Health; Associate Director, Center for Qualitative...
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November 2019

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