Medicine - Pediatrics
BangladeshExternal Bio Page
Cremini digital lung sounds in Bangladeshi children with clinical pneumonia
Pediatric pneumonia is a major cause of global mortality. Low-resource countries like
Bangladesh use non-specific clinical guidelines to diagnose pneumonia in children, and these
contribute to incorrect diagnoses, antibiotic over prescription, and suboptimal outcomes. Lung
auscultation is not included in current guidelines, largely due to subjectivity in sound
interpretation. Innovations that improve lung sound interpretation reliability could lead to better
diagnostic accuracy for children with respiratory illnesses in low-resource settings. The goal of
an inexpensive, portable, and automated lung sound interpretation device designed for children
is now possible thanks to advances in computerized sound analysis.
This research proposal is a collaborative effort between investigators at the Johns Hopkins
School of Medicine (Pediatrics and Internal Medicine), School of Public Health (International
Health and Epidemiology), and School of Engineering (Electrical and Computer Engineering) to
study an innovative digital auscultation device for children, the Cremini. Johns Hopkins sound
engineers developed the Cremini to address limitations in commercial digital stethoscopes that
hampered the lung sound recording quality of children in low-resource settings. We are unaware
of any other commercially available pediatric digital auscultation devices.
We aim to nest this project within an ongoing study of pneumococcal conjugate vaccine impact
in Sylhet, Bangladesh. Our primary goals are twofold, to assess the quality of lung sounds
collected by the Cremini from children 3-35 months old with clinical pneumonia, and to
investigate whether Cremini lung sounds predict radiographic pneumonia. Data generated from
this study will enable our group to compete for additional external funding.
Abdullah Baqui, JHSPH; William Checkley, SOM; Kate O'Brien, JHSPH; Megan Reller, SOM; James West, WSE.