Ying Zhang, MD PhD

School(s)

Molecular Microbiology and Immunology, Bloomberg School of Public Health

SciVal Website Link
Current Courses Link

Molecular Microbiology and Immunology, tuberculosis, mycobacteria, drug resistance, isoniazid, pyrazinamide, dormancy, persistence, L-form bacteria, drug and vaccine development, cancer stem cells

  • 1. Identified the first molecular mechanism of resistance to TB drug isoniazid (INH)

  •  Zhang, Y., Heym, B., Allen, B., Young, D., and Cole, S. (1992) The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis. [Comment] Nature (London) 358: 591-593. 

  • Zhang, Y., Garbe, T., and Young, D. (1993) Transformation with katG restores isoniazid sensitivity in Mycobacterium tuberculosis isolates resistant to a range of drug concentrations. Mol. Microbiol. 8: 521-524. 

  •  Zhang, Y. (2004). Isoniazid, In William N. Rom and Stuart Garay, ed, TUBERCULOSIS – 2nd Ed, Chapter 49, pp739-758, Lippincott Williams & Wilkins, A Wolters Kluwer Company, New York.

  • 2. Identified the molecular mechanisms of resistance and action for the unique persister drug pyrazinamide (PZA):

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Projects

Building an Enabling Environment for Vaccines in India...

This project, now in its second phase, aims to create an enabling environment for vaccines in India and contribute to...

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Identification and Enumeration of Pathogens in Drinking...

CWH researchers are using polymerase chain reaction and mass spectrometry technologies to develop a microbial isolation and...

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Nutrition Innovation Lab

"Poshan", which means good nutrition in Nepali is ongoing research that involves two interlinked large-scale research studies...

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Mpilonhle

Mpilonhle brings multi-dimensional services to adolescents in rural South Africa. Its objective is to reduce the very high...

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