Shyam Biswal, PhD MS

Position(s)

Director, Toxicology, Physiology and Molecular Mechanisms PhD Track

School(s)

Environmental Health Sciences, Bloomberg School of Public Health

Personal Website

SciVal Website Link
Current Courses Link

Environmental Health Sciences, cigarette smoke, lung diseases, inflammation, cancer, COPD, emphysema, asthma, environmental stress response

  • Kim JH, Thimmulappa RK, Kumar K, Cui W, Kumar S, Kombairaju P, Gaiano N, Zhang H, Margolick J, Matsui W, Macvittie T, Malhotra SV, Biswal S. NRF2-mediated Notch pathway activation enhances hematopoietic reconstitution following myelosuppressive radiation. J Clin Invest. 2014;3;124(2):730-41. Singh A, Happel C, Manna SK, Acquaah-Mensah G, Carrerero J, Kumar S, Nasipuri P, Wakabayashi N, Dewi R, Boros LG, Gonzalez FJ, Gabrielson E, Wong KK, Girnun G, Biswal S. Nrf2 regulates miR-1 and miR-206 to drive Tumorigenesis. J Clin Invest. 2013;123 (7) 2921-2934. Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction. Lam HC, Cloonan SM, Bhashyam AR, Haspel JA, Singh A, Sathirapongsasuti JF, Cervo M, Yao H, Chung AL, Mizumura K, An CH, Shan B, Franks JM, Haley KJ, Owen CA, Tesfaigzi Y, Washko GR, Quackenbush J, Silverman EK, Rahman I, Kim HP, Mahmood A, Biswal SS, Ryter SW, Choi AM. J Clin Invest. 2013;123(12):5212-30. Harvey C, Thimmulappa R, Sethi S, Kong X, Yarmus L, Brown R, Feller-Kopman D, Wise R, and Biswal S. (2011) Targeting Nrf2 Signaling Improves Bacterial Clearance by Alveolar Macrophages in Patients with COPD and in a Mouse Model.  Sci Transl Med 3(78):78ra32. Merchant A, Singh A, Matsui W, and Biswal S. (2011) The redox-sensitive transcription factor, Nrf2, regulates murine hematopoietic stem cell survival independent of ROS levels. Blood. 118:6572-6579. Wakabayashi N, Shin S, Slocum S, Agoston ES, Wakabayashi J, Kwak MK, Misra V, Biswal S, Yamamoto M, and Kensler TW. (2010) Regulation of Notch1 signaling by Nrf2: implications for tissue regeneration. Sci Signal 3(130):ra52. Yoshida T, Mett I, Bhunia A, Bowman J, Perez M, Zhang L, Gandjeva A, Zhen L, Chukwueke U, Mao T, Richter A, Brown E, Ashush H, Notkin N, Gelfand A, Thimmulappa R, Rangasamy T, Sussan T, Cosgrove G, Mouded M, Shapiro S, Petrache, Biswal S, Feinstein E, and Tuder R. (2010) RTP801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke induced pulmonary injury and emphysema. Nat Med 16(7):767-73. Sussan TE, Rangasamy T, Blake DJ, Malhotra D, El-Haddad H, Bedja D, Yates MS, Kombairaju P, Yamamoto M, Liby KT, Sporn MB, Gabrielson KL, Champion HC, Tuder RM, Kensler TW, and Biswal S. (2009) Targeting Nrf2 with the Triterpenoid CDDO-Imidazolide Attenuates Cigarette Smoke-Induced Emphysema and Cardiac Dysfunction in Mice. Proc. Natl Acad Sci. 106(1):250-5.

People

Joanne Katz, ScD MS,BSc

Associate Chair, Director of Academic Programs

Robert Bollinger Jr., MD MPH

Director, Johns Hopkins Center for Clinical Global Health Education (CCGHE); Associate Director, Johns Hopkins Center for Global...

Noreen Hynes, MD MPH

Director, Geographic Medicine Center of the Division of Infectious Diseases

Caitlin Kennedy, PhD MPH,BA

Co-Director, MPH concentration in Social and Behavioral Sciences in Public Health; Associate Director, Center for Qualitative...

Stefan Baral, MD MPH,MBA,MSc

Director, Key Populations Program

Yukari C. Manabe, MD

Associate Director of Global Health Research and Innovation
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Projects

Building an Enabling Environment for Vaccines in India...

This project, now in its second phase, aims to create an enabling environment for vaccines in India and contribute to...

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Nutrition Innovation Lab

"Poshan", which means good nutrition in Nepali is ongoing research that involves two interlinked large-scale research studies...

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Identification and Enumeration of Pathogens in Drinking...

CWH researchers are using polymerase chain reaction and mass spectrometry technologies to develop a microbial isolation and...

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Mpilonhle

Mpilonhle brings multi-dimensional services to adolescents in rural South Africa. Its objective is to reduce the very high...

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